Characters that cannot gain Red Heart containers will instead be given a Soul Heart ( Black Heart in the case of Dark Judas and Tainted Judas.) Eternal Hearts are placed in the second half of the last Red Heart container or Bone Heart, even when it is full (the Eternal Heart will overlap with the Red Heart in this case). They will also give a Red Heart container if two are collected on the same floor. When held until the next floor, Eternal Hearts will grant Isaac a Red Heart container. Blood Donation Machines and Devil Beggars will now deplete Isaac's last half or full Red Heart before depleting Soul Hearts. However, donating to a Blood Donation Machine or a Devil Beggar will deplete Red Hearts first as long as Isaac has more than half a Red Heart (a full heart in Womb and beyond).

Soul Hearts will be depleted before Red Hearts in most cases. Soul Hearts are not permanent once lost, they cannot be replenished, although new ones may be picked up. Soul Hearts are blue hearts that are added to the end of the health bar. Humbling Bundle and Equality! can replace this with a Double Heart. Isaac cannot have more Red Hearts than Red Heart containers, but certain Heart pickups can circumvent that limit. Hearts are the standard HP for most characters and can be found in several varieties. For other uses, see Heart (Disambiguation). If you found this article helpful and want more related content, check out our feature of other similar rogue-like games you can play.This article is about the pickup. That is everything you need to know on how to use items in Binding of Isaac. Pick Ups: These are miscellaneous collectibles in the game such as keys, hearts, coins and bombs that you get as loot from killing monsters and find on excavation.All you need to do is pick up a Trinet to instantly get its effect. Trinkets: These are special and rare items that act as a passive skill in their own place.These have the same key as Cards so you have to press Q. There is just one slot for Tarot Cards and Pills so you can only carry one at a time. Pills: These are more commonly found items that give you buffs that can also be used just once.You can use Tarot Cards by pressing the Q button. Tarot Cards share the same slot as Pills so you can only have one of either at once. Tarot Card: These mysterious cards that give you a random power-up to use once.Activated items can be used by pressing the SpaceBar on PC and L2 button for consoles. Activated Items: These are rare items that provide elusive power-ups that can be used multiple times with a cooldown time.Passive: These are unique permanent buffs applied to Isaac and applied automatically.Here are all the types of items in Binding of Isaac and how you can use them: Items help in various different ways depending on their types. Items are essential in this game because there are only a limited supply of bombs you can use to do damage and clear out areas.

Isaac 2 of hearts